*Diagnosis and confirmation of the indication are required for insurance-covered prescription. Use for cosmetic or fatigue-recovery purposes is self-pay. Please feel free to ask us for details.
A medical injection preparation made from human placenta. Based on a well-established preparation originally developed as an insurance-covered drug for chronic liver disease, it is also widely used as a self-pay treatment for cosmetic purposes, fatigue recovery, and improving menopausal symptoms.
A cosmetic treatment that subcutaneously injects placental extract directly into the face, targeting concerns such as sagging, wrinkles, enlarged pores, and dullness. Compared to a full-body injection, this allows for a more direct local effect on the skin.
The procedure is performed with a fine needle and takes about 5 minutes. There is almost no downtime, and makeup can be applied immediately afterward, making it an easy treatment for busy people.
The first systematic review to evaluate the efficacy of placental extract for menopausal symptoms. Searched 272 records across the MEDLINE, Scopus, and Embase databases, and analyzed 11 randomized controlled trials (RCTs) that met the inclusion criteria.
A multi-center, double-blind RCT comparing the efficacy of subcutaneous human placental extract injection against placebo in patients with chronic fatigue syndrome or chronic fatigue of unknown cause.
If you're unsure which to choose, please refer to the comparison table below. The doctor will recommend the best option based on your concerns and preferences.
| Item | Placenta Injection | Facial Placenta Injection |
|---|---|---|
| Main purpose | Improved liver function, fatigue recovery, overall skin beauty, relief of menopausal symptoms | Targeted improvement of facial sagging, wrinkles, pores, and dullness |
| Method of administration | Intramuscular injection (e.g. arm) | Subcutaneous injection (local to the face) |
| Characteristics | Broad effects throughout the body. An approach that works from the inside out. Typically requires visits 1-2 times a week | Direct facial administration for focused local care. Almost no downtime |
| Who it's for | Those who tire easily, are concerned about liver function, experience menopausal symptoms, or want to prevent overall aging | Those concerned about facial wrinkles or sagging, or who want to try a cosmetic procedure but have never had an injection before |
On your first visit, we will ask about your symptoms and goals and recommend the most suitable preparation, dosage, and frequency. We typically start with 1-2 visits per week and adjust based on your condition. Because the injection itself takes only a few minutes, it's an easy treatment to fit in before or after work.
Please note that receiving a placenta preparation means you will no longer be eligible to donate blood (per Japanese Red Cross Society regulations as of May 2026). If you donate blood regularly, please discuss this with us.
Even if you're not sure which type is right for you, please feel free to consult us.
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